Browsing by Author "Basar, Selda"

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Preventive Effect of the Neurodynamic Mobilization Technique on Delayed Onset of Muscle Soreness: A Randomized, Single-Blinded, Placebo-Controlled Study
(BMC, 2025) Sozlu, Ugur; Basar, Selda; Semsi, Rabia; Akaras, Esedullah; Dincel, Aylin Sepici
Background The neurodynamic mobilization (NM) technique is an intervention designed to restore homeostasis by mobilizing the nervous system and its surrounding structures. NM, through its physiological and biomechanical mechanisms, may play a role in modulating delayed Onset Muscle Soreness (DOMS) symptoms and regulating the emerging inflammatory response. The aim of this study was to determine the preventive effects of the NM technique on DOMS. Methods Thirty-four untrained males were randomized into the NM (n = 17) or placebo NM (n = 17) group. Femoral nerve NM and placebo NM techniques were performed for three weeks in both groups. All the participants subsequently performed 300 maximal isokinetic eccentric contractions of the dominant knee extensors. Markers of muscle damage (creatine kinase, lactate dehydrogenase) and inflammation (IL-6, TNF-alpha), as well as muscle soreness, pressure pain threshold (PPT) and muscle function, were measured at baseline; immediately before (pre) and after (0 h) the completion of the exercise-induced muscle damage (EIMD) protocol; and at 24, 48, and 72 h. Results Following the EIMD protocol, muscle soreness peaked at 24 h, while PPT reached its lowest level. The NM group exhibited significantly lower muscle soreness scores (F-3.160 = 5.436, p = 0.001) and higher PPT values (F-3.160 = 12.580, p 0.05). Conclusions Three weeks of femoral nerve NM applied to healthy untrained participants had positive effects on the possible negative consequences of DOMS. NM may help alleviate inflammation and muscle damage symptoms and shorten the overall recovery time following DOMS.
Translation, Cultural Adaptation, and Turkish Validation of the Tool 25-Question Geriatric Locomotive Function Scale
(BMC, 2025) Akaras, Esedullah; Basar, Selda; Koc, Kardelen; Kasali, Kamber
Background: The increasing prevalence of locomotive syndrome (LoS) among older adults underscores the necessity of valid and reliable assessment tools to facilitate early diagnosis and intervention. The 25-Question Geriatric Locomotive Function Scale (GLFS-25) is a widely used self-reported measure for evaluating locomotive dysfunction. However, a culturally adapted and validated version for Turkish older adults was lacking. This study aims to translate, culturally adapt, and validate the Turkish version of GLFS-25 to ensure its applicability in clinical and research settings. Methods: A cross-sectional study was conducted with 133 community-dwelling older adults (mean age: 75.3 +/- 7.2 years) in Turkey. The translation process followed international guidelines, including forward-backward translation, expert panel review, and pilot testing. The psychometric validation involved confirmatory factor analysis (CFA), internal consistency (Cronbach's alpha), test-retest reliability (intraclass correlation coefficient, ICC), and criterion validity. Correlations with established functional assessment tools such as the Barthel Daily Living Index, Instrumental Activities of Daily Living (IADL), and Activities-Specific Balance Confidence (ABC) Scale were examined. A receiver operating characteristic (ROC) curve analysis was performed to determine the optimal cut off score for detecting locomotive dysfunction. Results: The Turkish GLFS-25 demonstrated excellent internal consistency (Cronbach's alpha = 0.984) and test-retest reliability (ICC = 0.986). CFA confirmed a four-factor structure, similar to previous adaptations in Iran and China, supporting its construct validity. Strong correlations were observed between GLFS-25 scores and functional assessment tools (Barthel Index: r = -0.78, IADL: r = -0.72, ABC Scale: r = -0.65, p < 0.001), establishing its criterion validity. ROC analysis identified a cut off score of 16 for detecting locomotive dysfunction, with a sensitivity of 85.3% and specificity of 88.7%. Conclusions: The Turkish adaptation of GLFS-25 is a valid, reliable, and culturally appropriate tool for assessing locomotive dysfunction in Turkish older adults. Its strong psychometric properties and high correlation with functional mobility indicators suggest that it can be effectively integrated into geriatric healthcare and rehabilitation programs. Given the rapid aging of Turkey's population, this tool can support early detection, prevention strategies, and policy development to mitigate mobility-related disabilities.