WoS İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14901/698

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Citation - WoS: 6
Citation - Scopus: 8
Foliar Application of Cao Nanoparticles and Salicylic Acid on Medicago Sativa Seedlings Enhances Tolerance Against Fusarium Oxysporum
(Academic Press Ltd- Elsevier Science Ltd, 2022) Turgut, Buesra Albayrak; Bezirganoglu, Ismail
Crop losses caused by Fusarium oxysporum is getting serious around the world. Medicago sativa having huge cultivation area is one of the crops affected from this fungal pathogen, so it is an important issue to farmers. In order to struggle diseases, plants have many mechanisms such as secondary metabolite production, and path-ogenesis related protein synthesis including antimicrobial peptides (AMPs). AMPs are one the most important of them because they are specific for the pathogen types. In this study, it was reported that the assessment of the expression levels of MsDef1 and MsSN1 AMPs in M. sativa roots against F. oxysporum infection after pre-treatment of salycilic acid, CaO NPs and their combinations. MsDef1 and MsSN1 expression levels were significantly increased after foliar application of all SA concentration, 2 ppm CaO NPs and the combination of 1 ppm CaO NPs in 1 mM SA. The highest expression level was seen in 5 mM SA after 24 h of application. Also, it was examined antioxidant enzyme activities (CAT and SOD), and PPO and PAL enzyme, two important enzymes of the plant defense mechanism. PAL and PPO activities were slightly increased after the applications. According to our study, foliar application of SA and CaO NPs lead to significant increasing in the expression level of MsDef1 and MsSN1 against F. oxysporum, one of the most importat plant pathogens, which indicates the importance of the antimicrobial peptides in first line of defense in plants.
Citation - WoS: 12
Citation - Scopus: 12
The Influence of Y Contribution on Crystallographic, Topographic and Optical Properties of ZnO: A Heterojunction Diode Application
(Academic Press Ltd- Elsevier Science Ltd, 2015) Turgut, G.; Duman, S.; Keskenler, E. F.
Pure and yttrium (Y) doped ZnO samples were fabricated on micro slide glasses and p-Si wafers for device application via a simple and cheap sol-gel route using a spin coater. The characterization results of XRD, SEM and UV/VIS spectrophotometer revealed the films to have nano-sized ZnO hexagonal wurtzite structures with (002) preferential orientation and optical band gap values depending on Y doping ratio. The optical band of 3.285 eV for pure ZnO initially increased to 3.305 eV, 3.332 eV and 3.341 eV for 1 at.%, 2 at.% and 3 at.% Y incorporated ZnO films and then decreased to 3.271 eV and 3.258 eV for 5 at.% and 7 at.% Y contents. The electrical features of Al/ZnO:Y/p-Si/Al heterojunction structures were tested by I-V measurements. The heterojunction structures showed a rectifying behavior under dark condition. The Phi(b), and n values for the devices were identified by using I-V measurements. It was observed that the rectification ratio value of 3 x 10(4) calculated at +3.0 V for Al/ZnO:Y/p-Si (5 at.% Y doped ZnO) heterojunction structure was higher than most of n-ZnO/p-Si heterojunction devices reported in the literature. (C) 2015 Elsevier Ltd. All rights reserved.
Citation - WoS: 11
Citation - Scopus: 12
Investigations on the Crystalline, Topographic, Electrical and Optical Characteristics of Doubly Doped (Si + F) SnO2 Films Deposited Using Spray Pyrolysis Technique
(Academic Press Ltd- Elsevier Science Ltd, 2015) Turgut, G.; Thirumurugan, K.; Ravichandran, K.
Silicon and fluorine (Si + F) co-doped SnO2 thin films were deposited on soda lime glass substrate using the spray pyrolysis technique. The Si and F doping levels were varied from 0-10 and 2.5-10 in steps of 2.5 at. %, respectively. Initially the optimum doping level of Si is found (7.5 at. %) at which the film exhibits the minimum electrical resistivity value (4.23 x 10(-3) Omega cm) and then the doping level of F is varied and it is found to be better at 10 at. % on which it offers lower resistivity of 1.96 x 10(-4) Omega cm. From the structural studies, it is observed that the preferential orientation of all the films is along (2 1 1) plane irrespective of dopant and level of doping, but the peak intensity decreases as the doping level increases. The average transmittance of the all the films is found to be around 75% in the visible region and the optical band gap of the films are found to be in the region of 3.79-3.99 eV. (C) 2015 Elsevier Ltd. All rights reserved.
Citation - WoS: 51
Citation - Scopus: 60
Public Transit Usage and Air Quality Index During the COVID-19 Lockdown
(Academic Press Ltd- Elsevier Science Ltd, 2021) Sahraei, Mohammad Ali; Kuskapan, Emre; Codur, Muhammed Yasin
The people suffering from coronavirus have to lead unprecedented actions including limiting travel especially using public transportation. Therefore, lockdown measures and social distancing to decelerate the distribution of the COVID-19 has become the new norm. Nevertheless, improvement in the ambient air quality of the cities globally has appeared as a key advantage of this lockdown. There is a lack of research in the field of public transportation mobility and the Air Quality Index (AQI) during the COVID-19 lockdown globally. Consequently, this research aims to examine the overall impact of the public transit usage and ambient air quality, i.e. both AQI and indicatory air pollutants, during the lockdown in 12 countries. Data collections for analysis of public transportation usage and air quality status during the lockdown and one year before this period were carried out utilizing public transportation application Moovit and World?s Air Pollution. The results demonstrated that the lockdowns of 12 countries led to dramatically decreased human movements and public transit usage up to -90% until the end of March and it had no major changes until the end of May. In the case of ambient air quality, the average values of AQI in the 12 countries within lockdown 2020 for classes I(AQI:0-50), II(AQI:51-100), and III (AQI:101-150) increased by 12%, 9%, and 13% while for classes IV(AQI:151-200), V(AQI:201-300) and VI (AQI:301-greater) decreased by 10%, 27%, and 3% in comparison with the identical time throughout 2019. The results also indicate that throughout lockdown 2020, in the 12 countries, the percentages of indicatory air pollutants of PM2.5, PM10, SO2, CO, and NO2 were decreased by 16%, 21%, 41%, 48%, and 35% lower than those in the same time in 2019. Mechanism analysis and comparisons highlighted that the lockdowns of 12 countries led to decreased human mobility and improvement in the AQI around the world.
Citation - WoS: 54
Citation - Scopus: 65
Systems Biology Based Drug Repositioning for Development of Cancer Therapy
(Academic Press Ltd- Elsevier Science Ltd, 2021) Turanli, Beste; Altay, Ozlem; Boren, Jan; Turkez, Hasan; Nielsen, Jens; Uhlen, Mathias; Mardinoglu, Adil
Drug repositioning is a powerful method that can assists the conventional drug discovery process by using existing drugs for treatment of a disease rather than its original indication. The first examples of repurposed drugs were discovered serendipitously, however data accumulated by high-throughput screenings and advancements in computational biology methods have paved the way for rational drug repositioning methods. As chemotherapeutic agents have notorious side effects that significantly reduce quality of life, drug repositioning promises repurposed noncancer drugs with little or tolerable adverse effects for cancer patients. Here, we review current drug-related data types and databases including some examples of web-based drug repositioning tools. Next, we describe systems biology approaches to be used in drug repositioning for effective cancer therapy. Finally, we highlight examples of mostly repurposed drugs for cancer treatment and provide an overview of future expectations in the field for development of effective treatment strategies.

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