WoS İndeksli Yayınlar Koleksiyonu

Permanent URI for this collectionhttps://hdl.handle.net/20.500.14901/698

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Citation - WoS: 31
Citation - Scopus: 32
Acute and Chronic Effects of Aerobic Exercise on Serum Irisin, Adropin, and Cholesterol Levels in the Winter Season: Indoor Training Versus Outdoor Training
(Wolters Kluwer Medknow Publications, 2020) Ozbay, Serhat; Ulupinar, Suleyman; Sebin, Engin; Altinkaynak, Konca
The aim of this study is to investigate the acute and chronic effects of aerobic training performed indoors and outdoors on irisin, adropin, and cholesterol levels in winter. Thirty-two healthy males participated in this study. Participants were divided into two groups: outdoor group (n = 16) and indoor group (n = 16). They then performed 40-min aerobic running exercises 4 days/week for 18 weeks. The outdoor group trained at -5 degrees C-5 degrees C environmental temperature, while the indoor group trained at 21 degrees C-25 degrees C. Blood samples were collected before and after the 18-week training period and immediately after the first training. The results showed that single aerobic exercise induced minimal increase in serum irisin concentrations in both groups. In addition, irisin levels did not change in the outdoor group but significantly decreased in the indoor group after the 18-week training period. Aerobic exercise had no acute or chronic effects on serum adropin levels in the indoor group. However, the aerobic training caused a decrease in adropin levels chronically, but there was no acute effect after single aerobic exercise in the outdoor group. Furthermore, there was no acute effect on high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol, and total cholesterol after single aerobic exercise in both groups. However, after the 18-week training period, there was a significant increase in HDL-C levels in both groups. Moreover, the increase in HDL-C in the outdoor group was higher than in the indoor group. Thus, this study provides evidence for the beneficial chronic effects of aerobic exercise and cold on HDL-C levels as well as the beneficial acute effects on irisin concentrations.
Citation - WoS: 1
Citation - Scopus: 1
Adaptive Event Triggered Control of Nonholonomic Mobile Robots
(Springer International Publishing AG, 2021) Guzey, Mehmet
In this paper, the design of adaptive regulation control of mobile robots in the presence of uncertain robot dynamics and with event-based feedback is presented. Two-layer neural networks (NN) are utilized to represent the uncertain nonlinear dynamics of the mobile robots, which is subsequently employed to generate the control torque with event-sampled measurement update. Relaxing the perfect velocity tracking assumption, control torque is designed to minimize the velocity tracking error, by explicitly taking into account the dynamics of the robot. The Lyapunov's stability method is utilized to develop an event-sampling condition and to demonstrate the regulation performance of the mobile robot. Finally, simulation results are presented to verify theoretical claims and to demonstrate the reduction in the computations with event-sampled control execution.
Citation - WoS: 1
Citation - Scopus: 1
Advancing Pulmonary Embolism Detection with Integrated Deep Learning Architectures
(Springer, 2025) Biret, Can Berk; Gurbuz, Sukru; Akbal, Erhan; Baygin, Mehmet; Ekingen, Evren; Derya, Serdar; Tuncer, Turker
The main aim of this study is to introduce a new hybrid deep learning model for biomedical image classification. We propose a novel convolutional neural network (CNN), named HybridNeXt, for detecting pulmonary embolism (PE) from computed tomography (CT) images. To evaluate the HybridNeXt model, we created a new dataset consisting of two classes: (1) PE and (2) control. The HybridNeXt architecture combines different advanced CNN blocks, including MobileNet, ResNet, ConvNeXt, and Swin Transformer. We specifically designed this model to combine the strengths of these well-known CNNs. The architecture also includes stem, downsampling, and output stages. By adjusting the parameters, we developed a lightweight version of HybridNeXt, suitable for clinical use. To further improve the classification performance and demonstrate transfer learning capability, we proposed a deep feature engineering (DFE) method using a multilevel discrete wavelet transform (MDWT). This DFE model has three main phases: (i) feature extraction from raw images and wavelet bands, (ii) feature selection using iterative neighborhood component analysis (INCA), and (iii) classification using a k-nearest neighbors (kNN) classifier. We first trained HybridNeXt on the training images, creating a pretrained HybridNeXt model. Then, using this pretrained model, we extracted features and applied the proposed DFE method for classification. The HybridNeXt model achieved a test accuracy of 90.14%, while our DFE model improved accuracy to 96.35%. Overall, the results confirm that our HybridNeXt architecture is highly accurate and effective for biomedical image classification. The presented HybridNeXt and HybridNeXt-based DFE methods can potentially be applied to other image classification tasks.
Citation - WoS: 2
Algorithms for Joint Operation of Service Robotic Platform and Set of UAVs in Agriculture Tasks
(IEEE, 2017) Quyen Vu; Vinh Nguyen; Solenaya, Oksana; Ronzhin, Andrey; Guzey, H. Mehmet
The problems of designing a mobile robotic platform carrying a set of unmanned aerial vehicles and containing a container for a payload are considered. The issues of transportation of robots and joint activity of robots with various functions in solving agriculture problems are discussed. The conceptual model of a mobile platform design is given. The main stages of the algorithmic model of the joint operation of the mobile platform and the set of unmanned aerial vehicles brought to the working area are described.
The Alternative Methods for Disinfection of E. Coli
(Amer Inst Physics, 2016) Yetim, Tuba; Gormez, Arzu; Gurkok, Sumeyra
Recently, advanced oxidation processes have gained significant interest for bacterial inactivation. In the present study, the efficacy of sonolysis, photocatalysis and sonophotocatalysis was evaluated for disinfection of Escherichia coli O157:H7 strain. Sonophotocatalysis proved to be the most effective disinfection methods by generating greater amount of (OH)-O-center dot radical.
Citation - WoS: 31
Citation - Scopus: 31
Analysis of Factors Affecting Alcohol and Tobacco Concurrent Use by Bivariate Probit Model in Turkey
(Springer Heidelberg, 2021) Alkan, Omer; Abar, Hayri; Gencer, Ozge
Alcohol and tobacco use are risky factors that are associated with one another. High alcohol and tobacco use are significant public health problems with social and economic costs and one of the leading causes of preventable death and disease. The aim of this study was to determine the sociodemographic and economic factors on alcohol and tobacco concurrent use. In this study, a bivariate probit model was employed to determine the factors affecting alcohol and tobacco concurrent use among individuals aged 15 and above who were living in Turkey. The data used in this study was obtained from the Turkey Health Survey conducted in 2010, 2012, 2014, and 2016 by the Turkish Statistical Institute. The data were gathered from a total of 77,327 individuals. Empirical findings suggest that factors affecting alcohol and tobacco use were simultaneous. Also, the results revealed that several key variables such as age, gender, educational status, marital status, household monthly income level, and survey year were significant determinants of alcohol and tobacco concurrent use. Psychosocial support is significant for only tobacco use. In the last decade, a number of restrictions aimed to combat alcohol and tobacco use have been associated with reducing the usage habits of individuals. This is the first study that simultaneously compared both alcohol use and tobacco use using a Turkish sample.
Citation - WoS: 1
Citation - Scopus: 2
An Analysis of the Gods and Heroes in Ancient Mesopotamian Art
(Atatürk Univ, 2024) Topaloglu, Yasin; Kilic, Murat
Mesopotamia, the region between the Euphrates and Tigris rivers, was home to many civilizations such as Sumer-Akkadian, Babylonia, and Assyria. Mesopotamian culture is based on a common religious view and consists of theocratic states ruled first by priest-kings. Mesopotamia is one of the crucial geographies where history is illuminated by art. This art reflects the feelings and thoughts of people and provides important clues about their world. The Sumerians' invention of writing was a significant development, but other developments and innovations in Mesopotamia also affected ancient societies such as the Middle East and Anatolia. Art is at the forefront of these developments and innovations. Centers such as G & ouml;beklitepe, Kurupay, Nevali & Ccedil;ori, & Ccedil;ay & ouml;n & uuml;, Hac & imath;lar, and Eriha-Jericho contain early examples of this art. Works of art such as the Vultures Stele, Ur Standard, Uruk Warka Vase, Naram-Sin Victory Stele, and Lion Hunt Stele are essential examples for our subject with their depictions of gods, kings, and heroes. This visual art of Mesopotamia is critical to the history of the Ancient Age as it provides information that thousands of written documents cannot convey. In Mesopotamian art, where gods and heroes (kings) are seen from the Neolithic Age to the Early Bronze Age, the concepts of gods and kings occupy a central place in art. However, it is also evident that these depictions developed and changed over time. Looking at these depictions, it is understood that while gods represent the spirit world and beliefs, heroes (king or emperor) symbolize earthly power. In these works of art, heroes are usually depicted as hunters, warriors, or kings. This heroism, which extends to the claim of god or godhood, reflects new administrative powers, economic prosperity, and military development.
Citation - WoS: 2
Citation - Scopus: 3
Antibacterial Activity of Essential Oils Extracted from Satureja Hortensis Against Selected Clinical Pathogens
(American Institute of Physics, 2017) Gormez, Arzu; Yanmis, Derya; Bozari, Sedat; Gurkok, Sumeyra
The antibiotic resistance of pathogenic microorganisms has become a worldwide concern to public health. To overcome the current resistance problem, new antimicrobial agents are extremely needed. The aim of the present study was to evaluate the antibacterial activity of Satureja hortensis essential oils against seven clinical pathogens. Chemical compositions of hydro distillated essential oils from S. hortensis were analyzed by GS-MS. The antibacterial activity was investigated against Corynebacterium diphtheria, Salmonella typhimurium, Serratia plymuthica Yersinia enterocolitica, Y. frederiksenii, Y. pseudotuberculosis and Vibrio cholerae by the use of disc diffusion method and broth micro dilution method. The minimum inhibitory concentration (MIC) values of essential oils were found as low as 7.81 mu g/mL. Notably, essential oils of S. hortensis exhibited remarkable antimicrobial activities against the tested clinical pathogens. The results indicate that these essential oils can be used in treatment of different infectious diseases.
Citation - WoS: 100
Citation - Scopus: 116
Antidepressant Flavonoids and Their Relationship with Oxidative Stress
(Hindawi Ltd, 2017) Hritcu, Lucian; Ionita, Radu; Postu, Paula Alexandra; Gupta, Girish Kumar; Turkez, Hasan; Lima, Tamires Cardoso; de Sousa, Damiao Pergentino
Depression is a serious disorder that affects hundreds of millions of people around the world and causes poor quality of life, problem behaviors, and limitations in activities of daily living. Therefore, the search for new therapeutic options is of high interest and growth. Research on the relationship between depression and oxidative stress has shown important biochemical aspects in the development of this disease. Flavonoids are a class of natural products that exhibit several pharmacological properties, including antidepressant-like activity, and affects various physiological and biochemical functions in the body. Studies show the clinical potential of antioxidant flavonoids in treating depressive disorders and strongly suggest that these natural products are interesting prototype compounds in the study of new antidepressant drugs. So, this review will summarize the chemical and pharmacological perspectives related to the discovery of flavonoids with antidepressant activity. The mechanisms of action of these compounds are also discussed, including their actions on oxidative stress relating to depression.
Citation - WoS: 2
Citation - Scopus: 3
An Antidote for Imazalil-Induced Genotoxicity in Vitro: The Lichen, Dermatocarpon Intestiniforme (Korber) Hasse
(Akademiai Kiado Zrt, 2012) Turkez, H.; Aydin, Elanur; Aslan, A.
Imazalil (IMA), a commonly used fungicide in both agricultural and clinical domains, is suspected to produce serious toxic effects in vertebrates. In recent years, a number of studies have suggested that lichens might be easily accessible sources of natural drugs that could be used as a possible food supplement. Extensive research is being performed to explore the importance of lichen species, which are known to contain a variety of pharmacological active compounds. In this context, the antigenotoxic effect of aqueous Dermatocarpon intestiniforme (Korber) Hasse. extract (DIE) was studied against the genotoxic damage induced by IMA on cultured human lymphocytes (n = 6) using chromosomal aberration (CA) and micronucleus (MN) as cytogenetic endpoints. Human peripheral lymphocytes were treated in vitro with varying concentrations of DIE (0, 25, 50 and 100 mu g/ml), tested in combination with IMA (336 mu g/ml). DIE alone were not genotoxic and when combined with IMA treatment, it reduced the frequency of CAs and the rate of MNs. A clear dose-dependent decrease in the genotoxic damage of IMA was observed, suggesting a genoprotective role of DIE. The results of the present study suggest that this plant extract per se does not have a genotoxic potential, but can alleviate the genotoxicity of IMA on cultured human lymphocytes. In conclusion our findings may have an important application for the protection of cultured human lymphocyte from the genetic damage and side effects induced by medical and agricultural chemicals hazardous for people.
Citation - WoS: 3
The Antioxidant and Genotoxic Activities of Na2b4o7•10h2o in Vitro
(Parlar Scientific Publications (p S P), 2015) Celikezen, Fatih Caglar; Turkez, Hasan; Aydin, Elanur
Boron is known as a trace element for animals and humans. Sodium borates are used in some cosmetics, detergents, and chemicals of photography, adhesives and textile compounds. It was aimed to evaluate the antioxidant potentials and genotoxic risk of sodium borate (Na(2)B4O(7)center dot 10H(2)O) on human whole blood cultures in the extent of this study (n=5). Na(2)B4O(7)center dot 10H(2)O was administrated at wide range concentrations (0-1280 mu g/ml) to cultured human whole blood samples. The sister chromatid exchange (SCE), micronucleus (MN) and 8-oxo-2-deoxyguanosine (8-OH-dG) assays were performed to determine genotoxic effect. In addition, total antioxidant capacity (TAC) and total oxidative stress (TOS) levels were measured as biochemical parameters. Our results clearly demonstrated that all tested concentrations of Na(2)B4O(7)center dot 10H(2)O were not mutagenic. Moreover, Na(2)B4O(7)center dot 10H(2)O showed antioxidant activities especially at low concentrations (<40 mg/L) and the determined TOS levels did not change at all the concentrations of Na(2)B4O(7)center dot 10H(2)O. As a result, our data clearly demonstrated that Na(2)B4O(7)center dot 10H(2)O is non-genotoxic and it has a remarkable antioxidant potential in vitro.
Antioxidant Biochemical and Larvicidal Activity of Cyclamen Hederifolium Extracts
(Parlar Scientific Publications (P S P), 2022) Sak, Dilek; Turan, Murat; Mammadov, Tofik; Mammadov, Ramazan; Ili, Pinar; Davidov, Mahmudcon
This study aimed to determine the total phenolic and flavonoid contents of Cyclamen hederifolium ethanolic, methanolic and acetone extracts, and antioxidant activities of them, to investigate the potential safety/toxicity risks of the different parts and doses of the C. hederifolium ethanolic extracts using enzymes (ALT. ALP, and CRE), and the larvicidal effect of water extract against houseflies (Musca domestica) and mosquitoes (Culex pipiens). In vitro antioxidant activity of the extracts determined using DPPH and. ABTS assays. Total phenolic and flavonoid contents of the extract represented as mg GAE/g-extract and mg QE/g-extract, respectively. For enzyme assay, the blood of five different groups of rats were analysed on days 0, 15, and 30. The highest value with the lowest IC50 value in the DPPH test was obtained from the ethanolic extract of the above ground (AG) (0.83 0.00 ug/mL. The highest value with the lowest IC50 value in the ABTS test was obtained from the methanolic extract of the underground (UG) (0.16 0.00.tg/mL), Statistically significant increases in AG 1% group and significant decreases in UG 1% group were observed in ALT and ALP values (p < 0.05), The AG extract was found to be more toxic against M. domestica (30,45 + 2.78%) and Cr. pipiens (83.33 + 0.00%). Considering the ALT and ALP measurements, the increase in the values in AG 1% group over time indicates liver damage. It seems that UG 1% extract reduces liver enzyme levels, and it has increased larvicidal effect over time.
Citation - WoS: 1
Citation - Scopus: 1
Arc Routing Problem Approach for Reducing Exhaust Gas Emission in Road Transportation: A Case Study of Erzurum
(Parlar Scientific Publications (p S P), 2019) Codur, Merve Kayaci; Yilmaz, Mustafa; Codur, Muhammed Yasin
One of the sectors that have the greatest impact on greenhouse gas emissions around the world is the road transportation sector. For this reason, the studies carried out for the logistic activities of the enterprises and entrepreneurs in a way that will cause the least harm to the environment are accelerating day by day. Some processes are routinely carried out on the road to ensure both transportation safety and environmental regulation. One of these processes is the snow plowing process, which is frequently performed in winter months. There are several heavy-duty vehicles that using for snow plowing operations on the roads, and these vehicles are seriously releasing exhaust gases. Therefore, in this study, the measures reducing the adverse effects of exhaust emissions on the environment arising from road vehicles were analyzed by arc routing problem approach. As one of these measures, transportation planning of the vehicles traveling on the road network and the completion of the process by vehicles in the shortest distance is expected. The optimum routes of vehicles traveling on the roads are critically important in terms of cost, distance and environmental effects. In this study, multiple vehicle variants of k-Chinese Postman Problem (k-CPP), which is one of the most frequently used approaches of arc routing problems, are addressed. A new type called Balanced k-Chinese Postman Problem (Bk-CPP) that balances the workload among vehicles and that has an important role for real-world applications is developed. A bi-objective integer-programming model is presented. There are two objectives; to minimize the total distance covered, and to balance the workload in terms of distance traveled among vehicles as much as possible. The proposed Bk-CPP model is applied to a network of a part of Ataturk University campus in Turkey for snow plowing operations. Additionally, well-known arc routing test instances that are widely used in the literature are solved to demonstrate the effectiveness and applicability of the proposed Bk-CPP model. The results show that the optimum routes significantly outperform to reduce the amount of exhaust gas emissions.
Assessment of Element Concentration Distribution in Different Rat Organs by Wavelength Dispersive X-Ray Fluorescence: Effects of Aluminum Chloride
(Parlar Scientific Publications (p S P), 2018) Akbaba, Ugur; Arslan, M. Enes; Celik, Kubra; Turkez, Hasan; Akbaba, G. Bugra
Aluminum (Al) is present on earth surface has different chemical forms. It is a toxic metal and it may cause different disorders such as osteomalacia, microcytic anemia, Alzheimer and Parkinson's disease. Thus, it is very important to understand the effects of Al on different organs. In order to examine its accumulation, rats (male Wistar) were exposed to 5 mg/kg/day AlC1(3) through gavage method for 30 days. At the end of the process, heart, brain, kidney and skin were removed and dried under sunlight. The samples were analyzed on a sequential Wavelength Dispersive X-ray Fluorescence (WDXRF) spectrometer. The results indicate that Al accumulates significantly in the brain. These results can be associated with neurotoxin effects. Although this study focused on the accumulation of Al, the concentration changes of detected elements from Beryllium (Be) to Uranium (U) accumulations were analyzed. The current study has proved that the WDXRF method is a quick, inexpensive and effective method in toxicological studies.
Citation - WoS: 1
Astrakhan and Its Surroundings According to Yan Pototsky's Travel Notes
(Selcuk Univ, Inst Turkish Studies, 2023) Sever, Zafer
Considered one of the first travel writers of the modern era, Yan Pototsky is considered by his contemporaries a historian, linguist, geographer, archaeologist, naturalist, and scientist, and many other merits. Pototsky, who traveled to almost all Slavic lands, Europe, Asia, Africa, and many other places, wrote many articles after his travels. One of these travels is to Astrakhan, and the Caucasus made in 1797-1798. Pototsky devoted the first year of his trip to Astrakhan and its surroundings. This part was first published in the I and II issues of the Severny Archive Magazine which is published in St. Peterburg. Pototsky, who started his journey from Moscow on a spring day, first went to Serapta by land and then to Astrakhan in a ship. There is interesting information about other steppe peoples in this trip, especially Kalmyks, Kazakhs, Tatars, Cossacks, and Buddhists living in and around Astrakhan. Pototsky's journey is important in terms of showing the region's demographic structure at the end of the 18th century, being multicultural and multilingual. For this reason, the study will contribute to those who will research about the region in the historical and cultural context.
Citation - WoS: 2
Attitudes Towards Nutritional Sport Supplement of National and International Kickboxers
(Natl Cave Research & Protection Organization, India, 2020) Ulupinar, Suleyman; Ozbay, Serhat; Gencoglu, Cebrail; Ozkara, Abdullah Bora
This study aims to investigate the nutritional ergogenic aids attitudes levels of the active Turkish kickboxers in terms of gender, competition weight, competition category, education status, income levels, and the status of the kickboxers whether international athletes or not. The Attitude Scale toward Nutritional Sports Supplements (ATNSS) was used in this study, which consists of the sub-dimensions benefit, side effects and ethics, natural nutrition. The side effects, ethics and natural nutrition sub-dimensions of female athletes were significantly higher than male athletes. When the relationship between income level and ATNSS sub-dimensions was examined, the side effects and ethics sub-dimension was significantly lower in the athletes with low income than the athletes with middle and higher income. Examining ATNSS' sub-dimensions according to their university education levels, the benefit sub-dimensions scores of athletes studying at the faculty of sports sciences were significantly higher than the athletes who did not study in the sports departments. Further, the benefit sub-dimension scores of the international kickboxers were significantly higher, and the side effect and ethic and natural nutrition sub-dimension scores were significantly lower than the national kick boxers. Conclusively, it is thought that informing the kickboxers about nutritional ergogenic sports supplements may be important in terms of increasing awareness and sporting performance in this area.
Biathlon Performance: Heart Rate, Hit Rate, Speed and Physiological Variables
(Lahore Medical Research Center LLP, 2021) Atasever, Gokhan; Kiyici, Fatih; Bedir, Deniz; Agduman, Fatih
Aim: Biathlon is a sport that combines cross-country skiing and rifle shooting. The athlete is fast in the cross-country skiing section, in the gun shooting section, the heart rate should be low. This study aims to determine the hitting rate of the shots made with different training loads on low altitude in elite biathletes in terms of maximum speed and physiological variables. Methods: To evaluate shooting performances first with the resting pulse and then after 2.5 km skiing respectively with 50%, 70% and 100% pulse rate which is separately calculated for each athlete according to karvonen formula. Results: Our findings show that while there was negative relation between maximum speed and body fat there was a positive relation with lean body mass. It has been determined that low body fat percentage and high lean body mass are effective at the athletes' maximum speed and the pulse level with the highest target shooting accuracy rate was at rest and 70% in the second level. Conclusion: Since the pulse of the athlete who comes to the shooting area cannot be reduced to a resting level in a short time, focusing the 70% pulse zone may be beneficial in terms of shooting accuracy and acceleration after the shot. The lowest results in target shooting accuracy were seen at 50% and 100% loads.
Citation - WoS: 15
Citation - Scopus: 15
A Biomechanical Study of 4 Different Sternum Closure Techniques Under Different Deformation Modes
(Oxford University Press, 2017) Orhan, Suleyman Nazif; Ozyazicioglu, Mehmet Hamit; Colak, Abdurrahim
OBJECTIVES: This study experimentally compares the efficiency of the 4 most preferred sternal closure tehniques, in 3 different deformation modes of the chest. METHODS: Polyurethane sternum models fixed by conventional wiring, steel band, ZipFix band and figure-8 wiring are tested statically under lateral distraction, longitudinal shear and torsional deformation modes. As a result, load-deformation curves are obtained. The closure efficiency of the techniques is then compared with respect to allowable load (corresponding to 2 mm displacement), rigidity, rupture load and rupture displacement. A comparison in terms of cost and ease of application has also been presented. RESULTS: The highest allowable load and rigidity values in simple tension and longitudinal shear are obtained by the steel and ZipFix band techniques, respectively. In torsion mode, the highest allowable load is provided by the ZipFix band and the highest rigidty is attained by the steel band technique. The highest rupture loads under simple tension, longitudinal shear and torsion modes are observed in ZipFix, steel band and conventional wiring, respectively. Steel band closure provides the least rupture displacement in simple tension as well as torsion, whereas ZipFix bands give the smallest rupture displacements in longitudinal shear. However, in every loading mode there were no statistically significant differences in allowable load, rigidity and rupture load values between the closure methods, and only rupture displacement values were statistically different for each method. CONCLUSIONS: Our results showed that conventional wiring is the most advantageous closing method when compared to the others.
Citation - WoS: 4
Citation - Scopus: 5
Biosafety Evaluation of Nanoparticles in View of Genotoxicity and Carcinogenicity Studies: A Systematic Review
(Trans Tech Publications Ltd, 2013) Turkez, Hasan; Celik, Kubra; Cakmak, Bulent
Nanoparticles (NPs) are used in various forms in consumer products including, cosmetics, food packaging, textiles and also in air and water cleaning, production of electro chromic windows, or smart windows and gas sensors. Many NPs have also been evaluated for potential use in biomedical applications as efficient delivery carriers for cancer diagnosis and therapy. Nowadays, NPs are being developed to create fascinating nanotechnology products. To develop NPs for broad applications, potential risks to human health and the environment should be evaluated and taken into consideration. Again, to translate these nanomaterials to the clinic and industrial domains, their biosafety needs to be verified, particularly in terms of genotoxic and carcinogenic effects. To evaluate evidenced-based practices for NPs safety, we performed a systematic review of the published English-language literature. We performed a systematic keyword search of PubMed for original research articles pertaining to reports on assessment of risks due to carcinogenic and mutagenic effects by different NPs. We identified 362 original articles available for analysis. The included studies were published between 1993 and 2012. The in vivo or in vitro genotoxicity studies were performed on only 18 out of 148 kinds of NPs in industry today. Likewise, the carcinogenicity investigations were performed on only 14 out of 148 NPs. The 10 types of the NPs including some titanium, aluminium, carbon black and silver molecules were found to have both mutagenic and carcinogenic potential. The important finding was also that there is a lack of systematic assessment of the DNA damaging and carcinogenic potential of NPs in spite of their extensive use in nanotechnological applications.
Citation - WoS: 2
Cepstrum Coefficients Based Sleep Stage Classification
(IEEE, 2017) Oral, E. Argun; Ozbek, I. Yucel; Codur, M. Mustafa
This paper examines filterbank parameters to extract discriminative cepstrum coefficient from EEG signals for sleep stage classification using well-known Support Vector Machine (SVM) algorithm. The proposed method has three main stages as feature extraction, training and classification. In feature extraction step, features are obtained using linear frequency cepstrum coefficients (LFCC) of EEG signals. Then SVM classifier is trained based on the extracted features. In the final step of classification, the class of test subject is estimated by using the trained model. Experimental results show that about an average of 95 percent correct classification rate is achievable for three classes, and this is better than the compared results available in the literature.

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